Research record
Overview
Compound name: Human Chorionic Gonadotropin
Common abbreviation: hCG
Compound classification: Glycoprotein hormone
Brief factual description:
Human chorionic gonadotropin (hCG) is a naturally occurring glycoprotein hormone produced by placental trophoblast cells during pregnancy. It functions as a luteinizing hormone (LH) analog, binding to LH receptors to maintain progesterone production, support pregnancy, and regulate reproductive hormone synthesis.
Mechanism of Action
Primary biological targets: Luteinizing hormone/chorionic gonadotropin receptor (LHCGR)
Affected systems: Reproductive, endocrine
Receptor selectivity:
High affinity for LH receptors
Downstream signaling effects:
Activation of adenylate cyclase
Increased intracellular cAMP
Stimulation of steroidogenesis (progesterone, testosterone)




