Research record
Overview
Compound name: Human Growth Hormone Fragment 176–191
Common abbreviation: hGH Frag 176–191
Compound classification: Synthetic peptide fragment
Brief factual description:
hGH Fragment 176–191 is a specific amino-terminal fragment of human growth hormone consisting of amino acids 176 through 191. It was isolated based on evidence that this region retains lipolytic activity while lacking the growth-promoting effects of full-length hGH.
Mechanism of Action
Primary biological targets: Adipocyte lipid metabolism pathways
Affected systems: Metabolic, adipose tissue
Receptor selectivity:
Does not significantly activate the classical growth hormone receptor (GHR)
Downstream signaling effects:
Stimulation of lipolysis in adipose tissue
Inhibition of lipogenesis
No significant stimulation of IGF-1 production




